New Consumer Study: WATTS'UP® improves Sports Recovery
Recovery Enhanced with WATTS’UP® Citrus Extract, New Consumer Study Shows
In a recent consumer study, WATTS’UP® – our proprietary citrus flavonoid extract – demonstrated a positive effect on recovery in a group of trained kickboxers.
Study Design
Over the course of 7 days, 10 well-trained kickboxers supplemented daily with effervescent tablets containing WATTS’UP®. The aim was to assess recovery following intense physical exercise. For full details, download the consumer study here.
Promising Results Already After a Week
The results were clear: after just one week of supplementation, participants showed significantly faster heart rate recovery compared to their baseline performance without WATTS’UP®. This suggests that the citrus extract may help support faster recovery following high-intensity effort.
For full results and graphs, download the study here.
This study adds to the growing body of evidence supporting WATTS’UP®’s role in performance nutrition — not only in power capacity, as shown in previous clinical trials, but now also in recovery dynamics among strength and power athletes.
What are the best substitutes for caffeine? 2
What are the best substitutes for caffeine?
Last updated: June 28th, 2024
A wide variety of caffeine-containing products are available, ranging from coffee and tea to dietary supplements, sodas and energy drinks. However, consuming too much caffeine often leads to side effects such as stress, anxiety, and even sleeping problems. If you are looking for alternative products to boost energy levels and increase focus, Brainberry®, maca root, ginseng, Rhodiola, and Lion’s Mane are natural ingredients that can help you get through the day without side effects.
Why You Might Need a Caffeine Substitute
Coffee is a beloved beverage enjoyed by millions daily, whether for its rich flavor, energizing effects, or the social connections it fosters. While many drink coffee to feel awake, alert, and energetic, caffeine—the active ingredient responsible for these effects—isn’t without its drawbacks.
Caffeine is found in coffee, tea, energy drinks, and even dietary supplements, making it a popular choice for boosting energy levels and focus (1). However, despite its benefits, caffeine can also contribute to stress, anxiety, and insomnia (2). These side effects lead many people to seek alternatives that provide similar energy and focus benefits without the negatives.
Why Should You Substitute Caffeine with Another Ingredient?
The unique properties of caffeine make it an effective stimulant, but its potential downsides are worth considering. High caffeine consumption can disrupt sleep patterns, elevate stress levels, and increase feelings of anxiety. For these reasons, reducing caffeine intake and exploring natural substitutes has become a popular choice.
Below, we’ll introduce some of the best natural alternatives to caffeine that can help you feel energized and focused—without the jitters or stress.
Looking for a Caffeine Alternative?
The best substitutes for caffeine
1. Maca root
Maca is a plant that grows in Peru (also called Peruvian ginseng). It’s a plant that belongs to the brassica (mustard) family. It is traditionally used for nutritional and medicinal purposes. The plant is made into a powder that is often added to smoothies, juices, and shakes.
It has been used for centuries as a fertility enhancer in humans and animals, but now more benefits of consuming maca are being discovered. The benefits of maca root vary, and evidence shows it may help increase energy levels and improve mood.
Additionally, other findings show that maca can help against feelings of anxiety and stress. This makes Maca a good alternative to caffeine, which can have the opposite effect.
2. Ginseng
Like maca, ginseng is a herb made from the root of its plant. It has been one of the most important products for health care in Asia. There, it has been used to make traditional medicine for centuries.
There are different types of ginseng, which vary in the way they are grown and processed. White ginseng is dried naturally, while red ginseng is steamed before it is dried, which increases its efficacy. The most important compounds in ginseng are ginsenosides and gintonin [3].
Ginseng is one of the most popular caffeine substitutes. Various research demonstrated that this plant is able to improve brain functions, boost mood and memory, help against fatigue, and increase energy levels.
3. Brainberry® (Aronia berry extract)
Aronia berries are becoming increasingly popular among consumers because of their many demonstrated health benefits. Aronia plants are native to North America but are also commonly found in the Baltic region of Europe.
Brainberry® is an Aronia berry extract researched and developed by Solabia Nutrition. It was demonstrated that the daily consumption of Brainberry® is able to boost mental energy and focus without side effects. An ideal alternative if you want to get rid of caffeine!
The main constituent of Brainberry® is an anthocyanin called Cyanidin 3-O-galactoside, a powerful antioxidant that can improve brain health and support brain function
Everything you need to know about Brainberry®
4. Rhodiola
Rhodiola is a plant that can be found in Europe and Asia. Like ginseng and maca its root is consumed for health benefits. Rosavin and salidroside are believed to be its most profitable compounds.
Rhodiola has been used for many years and has been mostly recommended to treat headaches, hernias and has also been used as an astringent. Nowadays, rhodiola is often consumed by people during stressful times.
If you’re looking for a natural alternative to caffeine that reduces fatigue, rhodiola is a good option because it has been shown to improve symptoms in participants that suffered from chronic fatigue. The stress-lowering and energizing effects of rhodiola make it a great natural replacement for coffee.
5. Lion’s Mane
Lion’s Mane is a mushroom that can grow long hair-like strings that resemble a lion’s mane. It is often found in North America, Europe, and Asia. It consists for roughly 20% out of protein.
Lion’s Mane is increasingly studied. It has properties that are believed to be neuroprotective. That is because two novel nerve growth factors have been discovered in this mushroom [4].
Lion’s Mane has thus been said to have positive effects on the brain. It can improve memory and helps to lower feelings of stress and anxiety. This makes it an ingredient that can help consumers cut down on their caffeine consumption.
The bottom line
We all love a good cup of coffee in the morning. However, there are several reasons to reduce caffeine intake and look for a substitute. The aforementioned ingredients are good natural alternatives to caffeine as they can boost energy levels and brain functions, without having any anxiety or stress inducing effects.
6 Best Ingredients For Brain Health
6 Best Ingredients For Brain Health
Last updated: 13th December 2024
Are you looking for natural ways to boost your brainpower and enhance cognitive health? You’re in the right place! In this article, we dive into six ingredients that have the potential to support memory, focus, and overall brain function. From scientifically-backed nutrients to ancient remedies, discover how these compounds can help unlock your mental clarity and vitality.
What is a Healthy Brain?
The brain is an extraordinary organ, a complex network of firing neurons that serves as the command center for every decision and action we take daily. Despite making up just 2% of our body weight, the brain demands up to 20% of the body’s oxygen supply, highlighting its critical importance (1). To function optimally, it also relies on a steady intake of essential nutrients to fuel its processes—whether you’re awake or asleep.
One of the best diets for brain health is the Mediterranean diet,renowned for its rich variety of nutrient-packed foods. This diet includes brain-boosting staples like fresh seafood, vibrant fruits and vegetables, olives and olive oil, nuts, beans, and even moderate amounts of wine. Its diverse range of key nutrients has been linked to better cognitive function and long-term brain health.
By incorporating these nutrient-rich foods into your diet, you can support a healthy, high-performing brain for years to come.
Supplementing your diet for optimal brain health
Even the healthiest diet can benefit from the addition of targeted supplements, especially those designed to support brain health. While Italians famously adhere to the Mediterranean diet, they also lead Europe in supplement consumption—showcasing how even nutrient-rich diets can be enhanced. For individuals in other parts of the world with different dietary patterns, supplements provide an excellent opportunity to bridge nutritional gaps and optimize overall brain function.
In this article, we explore six of the most powerful ingredients to look for in brain health supplements. These compounds are backed by science and can help you maintain a sharp, healthy mind:
1. Berry Anthocyanins
Anthocyanins, a group of flavonoids, are the compounds responsible for the vibrant blue and purple hues in fruits like blueberries, raspberries, and acai berries. However, Aronia berries (chokeberries) outshine them all, boasting the highest anthocyanin content.
These powerful antioxidants enhance brain perfusion and neurotransmitter levels, supporting cognitive functions like memory, attention, and psychomotor speed (2, 3).
👉 Learn more about the health benefits of Aronia berries.
2. Phosphatidylserine
Phosphatidylserine (PS) is a crucial phospholipid in the brain, supporting cell protection and communication between neurons.
Efficiently absorbed as a supplement, PS crosses the blood-brain barrier, aiding cognitive functions such as memory, concentration, problem-solving, and motor skills. It’s widely available in supplements, often paired with intermediates like citicoline (4).
3. Choline
Choline, an essential nutrient, plays a vital role in neurotransmitter production, brain health, and amino acid metabolism. It’s especially important for populations prone to low levels, such as pregnant women and older adults (5).
Adequate choline intake supports cognitive functions and may reduce the risk of vascular dementia. Optimal levels ensure sufficient building blocks for acetylcholine, the key neurotransmitter for neuron communication (6).
4. Resveratrol
Resveratrol, a polyphenol found in grapes and wine, offers neuroprotective, anti-inflammatory, and cardiovascular benefits.
It improves blood flow to the frontal cortex, enhancing decision-making and nutrient delivery. Resveratrol also protects neurons by scavenging free radicals, reducing oxidative damage caused by reactive oxygen species (ROS) (7).
5. Docosahexaenoic Acid
DHA is a long-chain omega-3 fatty acid essential for brain health, found in fish, krill, and algae, as well as their oil supplements.
DHA supports neurological processes like neurotransmitter release and neuron differentiation. It’s particularly vital for the frontal lobes, which handle attention, planning, and problem-solving. Regular DHA intake ensures optimal brain function (8).
6. Ginkgo Biloba
Ginkgo biloba extract (GBE), derived from the tree’s dried leaves, has been used for centuries in traditional medicine across Asia.
Known for its antioxidant properties, GBE improves blood flow and neurotransmitter levels. It has shown efficacy in treating dementia and offers cognitive benefits even for healthy individuals (9).
💡 High daily doses (240mg+) are especially effective for cognitive support.
Take Home Message
Optimal brain health relies on a balanced diet and targeted supplementation. Antioxidants like berry anthocyanins and resveratrol protect neurons and enhance blood flow, while phosphatidylserine and choline support cell communication and neurotransmitter production. Omega-3 fatty acids, particularly DHA, boost cognitive functions in the brain’s frontal lobes, and Ginkgo biloba extract improves blood flow and offers neuroprotection. Combining these powerful ingredients can help maintain a sharp and resilient mind.
New data: WATTS’UP® aids in muscle recovery
New data: WATTS’UP® aids in muscle recovery
An exploratory in vitro study is published in collaboration with the Centre for Healthy Eating and Food Innovation at Maastricht University Campus Venlo, the Netherlands. The aim was to investigate the effect of hesperetin, the active ingredient of WATTS’UP®, on muscle regeneration in the presence of oxidative stress. In other words, this study mimicked the conditions of muscle fatigue after strenuous exercise and explored the benefits of hesperetin on myoblast differentiation and therefore muscle recovery.
WATTS’UP®: micronized hesperidin for sports performance
WATTS’UP® is a clinically validated extract from sweet orange, standardized for >90% highly bioavailable hesperidin. In previous proprietary clinical studies, WATTS’UP® has established its beneficial effects on power output and peak power. Many supplement brands in the EU and US have already included this ingredient in their sports nutrition formulas.
The study: Hesperetin but not ellagic acid increases myosin heavy chain expression and cell fusion in C2C12 myoblasts in the presence of oxidative stress (1).
Introduction
Skeletal muscle mass and function are expected to decline with age, resulting in reduced muscle strength. Muscle stem cells (satellite cells) get activated as a result of strenuous physical activity and muscle trauma. They proliferate and migrate as myoblasts to the injured muscle tissue to repair the myofibers. Normal physiological levels of oxidative stress are needed for the proper function of stem cells, however excessive amounts impair their functionality.
To combat this challenge, a diet or supplements rich in polyphenols could reduce oxidative stress and therefore aid in muscle repair. Such polyphenol is for example hesperidin (active form: hesperetin).
Methods:
Muscle cells were cultured with either hesperetin (sweet orange), ellagic acid (pomegranate) or a combination of both in the absence and in the presence of oxidative stress (menadione sodium bisulfate). More details in the full publication: https://www.frontiersin.org/journals/nutrition/articles/10.3389/fnut.2024.1377071/full
Results:
Hesperetin treatment in cells exposed to oxidative stress increased myosin heavy chain expression by 35% compared to oxidative stress alone (p<0.01) after 5 days.
Additionally, Treatment with 20 μM hesperetin in C2C12 cells exposed to oxidative stress increased cell fusion compared to oxidative stress alone(p=0.04) as well as control (p=0.02).
Take Home Message:
Hesperetin enhanced myosin heavy chain expression under oxidative stress conditions and promoted cell fusion both with and without oxidative stress exposure. These findings suggest that hesperetin holds potential as a nutritional strategy in supporting fatigued muscles after strenuous exercise. Enhanced myosin heavy chain expression may translate to direct muscle recovery because it is a key protein in muscle fibers responsible for contraction and force generation. Increased myosin heavy chain expression indicates muscle repair and growth, helping restore strength and function after injury or stress.
Hesperitin is the active ingredient in WATTS’UP®, a sweet orange extract clinically validated to support power output and exercise performance. This new data confirms the potential of WATTS’UP® to increase the value of sports nutrition formulas, especially ones targeting muscles recovery.
New Consumer Study: Improvements in Sleep Quality, GI, Psychological and Skin Health
New Consumer Study: Improvements in Sleep Quality, GI, Psychological and Skin health
The latest consumer study with MicrobiomeX®, a natural citrus flavonoid blend, sheds light into its beneficial effects on overall mental wellbeing, gastrointestinal symptoms, skin and sleep quality.
Connecting Gut Health with Whole-Body Wellness
Research increasingly shows that gut microbiota composition impacts various systems in the body through mechanisms like the gut-brain and gut-skin axes. MicrobiomeX® leverages the power of flavonoids to positively modulate the gut microbiome, delivering broad health benefits.
We partnered with iProbio, a leading Slovakian research company specializing in prebiotics, probiotics, and gut health, to delve into the unique relationship between gut microbiota, sleep quality, and overall well-being.
Study Design
Participants (n=57) in the study were asked to take 500 mg of MicrobiomeX® daily and complete self-assessment questionnaires at three key points: baseline, one month, and three months.
Promising Results Already After One Months
After one month of supplementation, participants reported significant (p<0.017) improvements in:
- Enhanced psychological well-being
- Better skin appearance
- Reduced digestive symptoms
- Improved sleep quality
Take Home Message
These results were sustained after three months of supplementation. They reinforce the role of gut health as a cornerstone of overall well-being and highlight MicrobiomeX® as a natural, effective solution for improving skin and sleep quality.
Preliminary results: Brainberry® improves executive function
New preliminary results: Brainberry® significantly improves executive function
New preliminary data sheds light into the effect of Brainberry® on executive function. In our latest clinical study, we assessed executive function and cognitive performance, reflected via the spatial working memory test.
Solabia Nutrition announces preliminary results from a recent clinical study that demonstrate the potential of Brainberry®, our innovative aronia extract ingredient, to significantly improve executive function. This early data adds to the growing body of evidence supporting Brainberry®’s role in cognitive health, specifically targeting areas essential for multitasking and managing daily activities.
Anthocyanins, the key active compounds in Brainberry®, are abundant in aronia berries and have shown promise in supporting neuroprotective effects. Known for their ability to cross the blood-brain barrier, anthocyanins can directly influence brain function and have been studied extensively for their role in potentially improving brain signaling and consequently – executive function.
Study Design and Preliminary Findings
The study, a randomized, double-blind, placebo-controlled, cross-over trial, evaluated the effects of Brainberry® in middle-aged subjects. This demographic is particularly vulnerable to cognitive decline, making Brainberry®’s potential impact especially meaningful.
The results indicate that Brainberry® may support executive function, a crucial component of working memory and multitasking ability.
About Solabia Nutrition
Solabia Nutrition, based in Maastricht, Netherlands, develops and supplies proprietary bioactive formulations to the health and sports nutrition industry. All Solabia Nutrition’s products are clinically tested and from natural origin. The main focus areas are gut microbiome, brain health, energy & vitality and skin health.
Feel free to contact via contact@solabia.com for more information on the possibilities our ingredients have to offer.
Meet us at in-Vitality 2024
Meet us at in-Vitality 2024
Are you ready for in-Vitality 2024? We are looking forward to be in Milano!
It is time for the biggest Nutraceutical Event in Italy!
in-Vitality 2024 is taking place from 20-21st November in Milano. Join us to explore our latest preliminary data with Bonolive® for women’s health and Brainberry® for executive function!
We look forward to seeing you there!
Book a meeting!
What are the best substitutes for caffeine?
What are the best substitutes for caffeine?
Last updated: June 28th, 2024
A wide variety of caffeine-containing products are available, ranging from coffee and tea to dietary supplements, sodas and energy drinks. However, consuming too much caffeine often leads to side effects such as stress, anxiety, and even sleeping problems. If you are looking for alternative products to boost energy levels and increase focus, Brainberry®, maca root, ginseng, Rhodiola, and Lion’s Mane are natural ingredients that can help you get through the day without side effects.
Why should you substitute caffeine with another ingredient?
Most people drink coffee regularly. It is consumed because people like the taste or because of the social aspects to drinking coffee. Even though there are many ways to improve your focus, coffee is often consumed because it makes people feel more awake, alert, and energetic.
Of course, coffee is a source of caffeine, which is the ingredient that gives coffee its effects. There are other drinks that contain caffeine, and some people even take dietary supplements containing caffeine to boost their energy levels during the day or for their workout. [1].
Besides positive effects, consumption of caffeine may also have some downsides. These include giving people feelings of stress and anxiety. Besides increasing these feelings, caffeine consumption could also lead to insomnia [2].
Caffeine is unique in its function, but these adverse effects are a reason for people to reduce the intake of caffeine and look for alternative ingredients. Here are some suggestions of natural substitutes that make you feel awake and help you focus, without leaving you feeling stressed.
The best substitutes for caffeine
1. Maca root
Maca is a plant that grows in Peru (also called Peruvian ginseng). It’s a plant that belongs to the brassica (mustard) family. It is traditionally used for nutritional and medicinal purposes. The plant is made into a powder that is often added to smoothies, juices, and shakes.
It has been used for centuries as a fertility enhancer in humans and animals, but now more benefits of consuming maca are being discovered. The benefits of maca root vary, and evidence shows it may help increase energy levels and improve mood.
Additionally, other findings show that maca can help against feelings of anxiety and stress. This makes Maca a good alternative to caffeine, which can have the opposite effect.
2. Ginseng
Like maca, ginseng is a herb made from the root of its plant. It has been one of the most important products for health care in Asia. There, it has been used to make traditional medicine for centuries.
There are different types of ginseng, which vary in the way they are grown and processed. White ginseng is dried naturally, while red ginseng is steamed before it is dried, which increases its efficacy. The most important compounds in ginseng are ginsenosides and gintonin [3].
Ginseng is one of the most popular caffeine substitutes. Various research demonstrated that this plant is able to improve brain functions, boost mood and memory, help against fatigue, and increase energy levels.
3. Brainberry® (Aronia berry extract)
Aronia berries are becoming increasingly popular among consumers because of their many demonstrated health benefits. Aronia plants are native to North America but are also commonly found in the Baltic region of Europe.
Brainberry® is an Aronia berry extract researched and developed by BioActor. It was demonstrated that the daily consumption of Brainberry® is able to boost mental energy and focus without side effects. An ideal alternative if you want to get rid of caffeine!
The main constituent of Brainberry is an anthocyanin called Cyanidin 3-O-galactoside, a powerful antioxidant that can improve brain health and support brain function
If this sparked your interest, you can find out everything you need to know about Brainberry®, brain health and improving your focus here.
4. Rhodiola
Rhodiola is a plant that can be found in Europe and Asia. Like ginseng and maca its root is consumed for health benefits. Rosavin and salidroside are believed to be its most profitable compounds.
Rhodiola has been used for many years and has been mostly recommended to treat headaches, hernias and has also been used as an astringent. Nowadays, rhodiola is often consumed by people during stressful times.
If you’re looking for a natural alternative to caffeine that reduces fatigue, rhodiola is a good option because it has been shown to improve symptoms in participants that suffered from chronic fatigue. The stress-lowering and energizing effects of rhodiola make it a great natural replacement for coffee.
5. Lion’s Mane
Lion’s Mane is a mushroom that can grow long hair-like strings that resemble a lion’s mane. It is often found in North America, Europe, and Asia. It consists for roughly 20% out of protein.
Lion’s Mane is increasingly studied. It has properties that are believed to be neuroprotective. That is because two novel nerve growth factors have been discovered in this mushroom [4].
Lion’s Mane has thus been said to have positive effects on the brain. It can improve memory and helps to lower feelings of stress and anxiety. This makes it an ingredient that can help consumers cut down on their caffeine consumption.
The bottom line
We all love a good cup of coffee in the morning. However, there are several reasons to reduce caffeine intake and look for a substitute. The aforementioned ingredients are good natural alternatives to caffeine as they can boost energy levels and brain functions, without having any anxiety or stress inducing effects.
What are the benefits of hormone-free products?
What are the benefits of hormone-free supplements?
What Are Hormone-Free Supplements?
Hormone-free supplements are products that do not contain any synthetic or natural hormones. Unlike some supplements that include hormones like testosterone, estrogen, or HGH (human growth hormone), hormone-free supplements rely on vitamins, minerals, herbal extracts, amino acids, and other natural compounds to support the body’s functions.
Key Benefits
- Reduced Risk of Side Effects. Hormone-based supplements can lead to a range of side effects, including hormonal imbalances, mood swings, and even severe health issues. Hormone-free supplements eliminate these risks, providing a safer alternative for those looking to enhance their health and wellness (1). This is specifically popular among postmenopausal women (2).
- Natural Support for Body Functions. Hormone-free supplements often contain natural ingredients that support the body’s own hormone production and balance. For instance, adaptogenic herbs like ashwagandha and rhodiola can help the body manage stress and maintain hormonal equilibrium naturally. This holistic approach ensures that the body’s systems work synergistically without external hormonal interference.
- Enhanced Safety and Regulation. Supplements free from hormones are generally subject to fewer regulatory concerns compared to their hormone-containing counterparts. This often results in higher safety standards and fewer risks associated with their consumption. Consumers can feel more confident in the purity and safety of hormone-free products.
- Broad Accessibility. Hormone-free supplements are suitable for a wider audience, including individuals with hormone-sensitive conditions, pregnant, breastfeeding or menopausal women, and those who prefer to avoid any potential hormonal interference due to personal or medical reasons. This inclusivity ensures that more people can benefit from supplements without adverse effects.
- Support for Long-Term Health Goals. Because hormone-free supplements focus on natural ingredients, they are better suited for long-term use. Whether you’re looking to boost your immune system, improve your cognitive function, or enhance your physical performance, these supplements provide sustainable support without the need for cycling or discontinuation due to side effects.
Conclusion
Hormone-free supplements offer a compelling alternative for anyone looking to improve their health and wellness safely and naturally. By reducing the risk of side effects, supporting the body’s natural functions, adhering to high safety standards, and being accessible to a broad audience, these supplements stand out as a superior choice. As the demand for natural health solutions continues to grow, hormone-free supplements are likely to become even more popular, helping individuals achieve their health goals without compromising their well-being.
Meet us - Nutriform Business Days 2024
Meet us at Nutriform Business Days 2024
Our team is looking forward to attending Nutriform Business Days again this year!
We are pleased to visit the Nutriform Business Days from 18th till 20th June 2024 in France. Let’s meet and explore our range of premium health ingredients. Book a meeting below:
Book a meeting!
If you are in search for the perfect ingredient to finish your product formula, our booth is the right place to stop by. Our ingredients are extracted via clean production processes from specific raw materials. We introduce a few examples here:
- AstaPure® contains natural astaxanthin for cellular health. This powerful anti-oxidant is a great fit for an anti-aging product formula.
- AlgaSense®, a whole powder from micro algae, is the perfect fit for products targeting stress management, relaxation and mental health.
- Our award-winning Bonolive® is 100% natural extract from freshly pruned olive leafs, targeting women’s health and more specifically women in menopause. Bonolive® is fully backed-up by science and is the winner of the Innovation in Women’s Health Award by NutraIngredients!
- Brainberry® is our well-known aronia extract for brain fitness. As a true winner of the Nootropics Ingredients Idol award in 2023, Brainberry® is clinically-validated to boost focus, memory and eye-hand coordination.
- WATTS’UP® is a citrus extract with high bioavailability of Hesperidin. Clinical data showcases the benefits of WATTS’UP® for endurance and strength.
