Everything you need to know about Bonolive® and women's health
Everything you need to know about Bonolive® and women’s health
How do we define women’s health?
Woman’s health encompasses a range of physical, emotional, and mental aspects. Good health allows women to engage in daily activities with ease and vitality. It enables them to pursue their goals, whether personal or professional, without being limited by health issues. Hence, women’s quality of life is largely dependent on their health and mental status (1, 2).
A pivotal milestone in a woman’s life is the menopause, primarily characterized by hormonal fluctuations, particularly a decrease in oestrogen levels. This hormonal imbalance may have implications for women’s physical and mental health. However, with proper support and a holistic approach, the individual needs of each woman can be catered for.
How can we support women’s health (particularly during menopause)?
Women’s quality of life benefits from a holistic approach, including a comprehensive and integrated plan that addresses physical, mental, emotional, and social aspects of well-being (3). The top 3 strategies to support women’s health are listed below:
- Nutrition: Encouraging a balanced and nutritious diet is fundamental to women’s health. Emphasize whole foods, plenty of fruits and vegetables, lean proteins, healthy fats, and whole grains. Proper nutrition supports hormone balance, bone health, immune function, and overall vitality (4).
- Regular Exercise: Physical activity is essential for maintaining a healthy weight, reducing the risk of chronic diseases, improving mood, and enhancing overall well-being (5). It is advisable for women to engage in regular exercise that they enjoy, whether it’s walking, swimming, yoga, or strength training.
- Stress Management: Chronic stress can negatively impact women’s health. Teach stress management techniques such as mindfulness meditation, deep breathing exercises, yoga, or progressive muscle relaxation. Encouraging women to prioritize self-care activities would help them relax and unwind.
Exploring nutritional solutions for women’s health
As explained above, nutrition is a top priority to maintain and support health status. If we zoom in on women’s needs during peri- and post-menopause, we can explore in more detail what are the micronutrients that could provide a benefit during this stage of life. Typically, menopause is accompanied by acute symptoms such as bloating, night sweats, hot flashes, and long-term ones like loss of bone mineral density or imbalance in blood lipid profile.
Fortunately, there are quite a few nutritional strategies to explore in terms of lowering the risk of the above-mentioned conditions (6). For example, the sufficient intake of omega 3 and 6 fatty acids (7) is important for lipids metabolism as well as skin health. Furthermore, vitamin D (8) contributes to mineral turnover and bone health. In addition, olive polyphenols like oleuropein have great potential to support women in menopause by lowering the risk of bone loss and alleviating joint pain (9, 10).
What is oleuropein?
Oleuropein is the primary polyphenol found in olives and olive leaves (11). It contributes to the bitter taste of olives, especially the unripe ones. This compound has gained recent attention due to its potential health benefits for the human body such as anti-inflammatory and antimicrobial properties (12). Research suggests that it could support cardiovascular health by improving blood lipid levels. Oleuropein is also studied for its potential to aid bone health and skin health as it may reduce chronic inflammation. Moreover, Solabia Nutrition is the pioneer in research innovations with oleuropein and it is now under investigation for supporting women’s health, especially during and post-menopause.
How can oleuropein support women’s health?
Oleuropein may offer several potential benefits for women’s health during various stages of life, including menopause. Here’s how oleuropein can support women’s health:
- Bone Health: During menopause, women are at an increased risk of osteoporosis due to declining estrogen levels. Oleuropein has been shown to promote bone health by stimulating osteoblast activity (cells responsible for bone formation) and inhibiting osteoclast activity (cells responsible for bone resorption) (13). By supporting bone density and strength, oleuropein may help reduce the risk of osteoporosis and fractures in postmenopausal women.
- Cardiovascular Health: Cardiovascular risk increases after menopause, partly due to changes in hormone levels. Oleuropein has been found to have cardioprotective effects, including lowering blood pressure, reducing LDL cholesterol levels, and improving endothelial function (the function of blood vessel lining) (14). These benefits may help support heart health in women, particularly postmenopausal women.
- Anti-inflammatory Effects: Menopause is associated with increased inflammation in the body, which may contribute to various health issues such as joint pain, cardiovascular complications, and cognitive decline. Oleuropein has potent anti-inflammatory properties that can help reduce inflammation and oxidative stress, potentially alleviating symptoms and reducing the risk of chronic diseases associated with inflammation.
- Immune Support: The immune system can undergo changes during menopause, potentially leading to increased susceptibility to infections and immune-related conditions. Oleuropein exhibits antimicrobial properties and may help support immune function by inhibiting the growth of bacteria, viruses, and fungi (14). By bolstering the immune system, oleuropein may contribute to maintaining women’s health and resilience to infections.
- Hormonal Balance: Although more research is needed, some studies suggest that oleuropein may potentially help alleviate menopausal symptoms such as hot flashes, mood swings, and skin dryness by modulating hormone levels.
- Skin Health: oleuropein holds promise in lowering skin inflammation and supporting skin hydration due to its moisturising and antimicrobial properties (14, 15). vigorous research is currently ongoing in this area, as technological advancements allow for accurate monitoring of improvements in skin health parameters.
Is oleuropein scientifically proven to support women?
There are numerous clinical studies assessing the effects of oleuropein. However, BioActor is the first and only to design clinical studies in the context of women’s health. Three publications in international peer-reviewed journals are testimony of BioActor’s trailblazing research for women’s health. So far, oleuropein emerged as a promising ingredient to support women peri- and post-menopause.
- Firstly, a 12-month oleuropein intake resulted in a significant increase in osteocalcin, a marker for bone formation (12). The intervention group also maintained bone mineral density. Additional outcomes were the significant reduction in LDL-cholesterol and total triglycerides in the intervention group, compared to placebo.
- Secondly, pain during walking was significantly decreased after 6 months intervention compared to baseline (16). Importantly, oleuropein intake was well tolerated, therefore it may be considered for long-term intake to relieve joint discomfort and improve mobility.
- Moreover, postmenopausal women exhibited elevated blood plasma concentrations of Bonolive® metabolites. These findings suggest that the bioavailability of Bonolive® is particularly high in post-menopausal women compared to pre-menopausal women (17). Moreover, MDA a marker for antioxidant status significantly improved in post-menopausal women.
Overall, oleuropein has already shown excellent potential in supporting women’s health and menopause concerns. Therefore, our research group continues to investigate the effects of this ingredient on factors related to women’s health and menopause.
What is Bonolive®?
Bonolive® is Solabia Nutrition’s patented olive leaf extract standardized for high levels of oleuropein. This all-natural ingredient is clinically validated in post-menopausal women to support women’s health during post-menopause, notably by:
- Enhancing the number and activity of bone-producing cells (osteoblasts)
- Stabilizing bone mineral density (18)
- Improving blood lipids/lowering bad cholesterol
- Improving mobility/reducing joint pain
- Alleviating menopause symptoms related to mood and skin appearance (19, 20).
The history of Bonolive®
It all started with the breakthrough research of Professor Veronique Coxam on the bone protective properties of oleuropein at the French research institute INRA. Her colleague Marie-Noelle Horcajada continued working on the joint health benefits of Bonolive® at Nestlé Health Science. In parallel, BioActor’s CSO, Dr Yala Stevens and principal scientist Maria Imperatrice have been spearheading the research on Bonolive’s bioavailability and peri-menopause-related effects. More than 150 women took part in our studies as volunteers.
How are the olive leaves sourced?
Olive leaves provide the oleuropein present in Bonolive®. The olive plantation that provides the leaves for Bonolive® is situated near Cordoba, Spain. During the pruning season, the fresh leaves are collected and stored in a special environment to preserve the oleuropein content for extraction. This is an upcycling process, with the olive leaves being a clean and environmentally friendly source of oleuropein for Bonolive®.
Who can benefit from taking Bonolive®?
Bonolive® is a high-quality, 100% clean and scientifically backed ingredient, designed for women by women. Bonolive® targets specifically women in peri- and post-menopause, who need tailored support throughout this important life stage (21). Our latest consumer study suggests that women experiencing acute symptoms such as hot flashes, mood swings, and night sweats may notice improvements after just two weeks of use (22).
Easy formulation options with Bonolive®
Bonolive® is a great addition to any product formulation targeting women’s health, specifically menopause concerns. It has a convenient clinically validated dose of 250 mg which fits quite well in capsules. This ingredient is also lipids- and water soluble and can be formulated into softgels, effervescent tablets or beverages. It is also suitable for direct compression in the form of tablets.
Current products on the market often combine Bonolive® with other minerals, vitamins and botanicals suitable to support women’s health such as calcium, magnesium, iron, vitamins B, C & D etc. Our team can also offer formulation advice and guidance according to your specific projects.
Bonolive® is a safe solution for menopause support
Moreover, Bonolive® is well tolerated and suitable for long-term consumption to support menopausal women. Bonolive does not contain oestrogens, as opposed to isoflavones. BioActor commissioned extensive safety studies with Bonolive that have been published in a peer-reviewed journal. Recently, the US FDA approved the GRAS status of Bonolive for inclusion in functional foods and beverages, further affirming its high quality and safety standards.
Bonolive® wins a prestigious Women's Health Award
Bonolive® is the winner in Innovations in Women’s Health NutraIngredients Award!
Solabia Nutrition’s revolutionary ingredient, Bonolive®, selected as a winner for NutraIngredients Award in Innovation for Women’s Health!
Solabia Nutriton is proud to announce that Bonolive® won the prestigious NutraIngredients Award in Innovation for Women’s Health! Bonolive®’s exceptional contributions to women’s wellness have garnered recognition from industry experts and consumers alike.
Bonolive® is Solabia Nutrition’s patented olive leaf extract, standardized for high levels of oleuropein. It proudly stands as the only oleuropein ingredient patented specifically for women’s health, setting a new standard in innovation. This achievement is well deserved as Bonolive® has undergone several clinical trials in women, particularly during menopause, demonstrating its profound efficacy in supporting their health. Developed by an entirely female-led team, Bonolive® embodies a commitment to women’s wellness like no other.
This achievement underscores Solabia Nutrition’s commitment to advancing nutritional science and empowering individuals to live healthier, more vibrant lives.
We extend our heartfelt gratitude to the NutraIngredients Awards panel for this esteemed recognition!
Feel free to contact us for more information on the possibilities Bonolive® has to offer.
Further information can be found on: www.bonolive.com
MEET US - VitaFoods Europe 2024
Meet us at VitaFoods Europe 2024
Solabia Nutrition is exhibiting again at VitaFoods Europe 2024 in Geneva! We are looking forward to welcoming you to our booth H142!
We are looking forward to exhibiting at VitaFoods Europe from May 14th to 16th, 2024. Come visit us at booth H142 and explore our range of premium health ingredients.
This year, we are also organising a Hydration Station to showcase the natural taste and color of our water-soluble ingredients. You will have the opportunity to try some creative cocktails in our own bar area!
Book a meeting!
If you are in search for the perfect ingredient to finish your product formula, our booth is the right place to stop by. Our ingredients are extracted via clean production processes from specific raw materials. We introduce a few examples here:
- AstaPure® contains natural astaxanthin for cellular health. This powerful anti-oxidant is a great fit for an anti-aging product formula.
- AlgaSense®, a whole powder from micro algae, is the perfect fit for products targeting stress management, relaxation and mental health.
- Bonolive® is our 100% natural extract from freshly pruned olive leafs, targeting women’s health and more specifically women in menopause. Bonolive® is fully backed-up by science, researched by women for women.
- Brainberry® is our well-known aronia extract for brain fitness. As a true winner of the Nootropics Ingredients Idol award in 2023, Brainberry® is clinically-validated to boost focus, memory and eye-hand coordination.
- WATTS’UP® is a citrus extract with high bioavailability of Hesperidin. Clinical data showcases the benefits of WATTS’UP® for endurance and strength.
Nutritional strategies to relieve menopause symptoms
Nutritional strategies to relieve menopause symptoms
Last updated: March 22nd, 2024
During and after menopause, many women experience uncomfortable symptoms such as bloating, hot flashes, and night sweats. While hormonal therapy can help alleviate symptoms, it may also have side effects. Therefore, more attention is being given to changes in diet or the use of natural supplements. This article will explore nutritional strategies that may provide relief from menopause symptoms.
Foods to alleviate menopause symptoms
As women approach menopause, a lot of changes occur. Their estrogen levels decrease, leading to various symptoms such as bloating, night sweats, anxiety, or depression.
Menopause can also increase the risk of cardiovascular diseases and bone loss, which are commonly ignored. However, making some dietary changes can be an effective and easy way to alleviate these symptoms. In this article, we will discuss five foods that can help ease menopause symptoms.
1. Fish rich in n-3 PUFAs for menopause support
Fish is a great source of healthy and essential fatty acids, including omega-3 polyunsaturated fatty acids (n-3 PUFAs) that have protective effects and anti-inflammatory actions. These fatty acids are found in fatty fish like salmon and some algae species.
Research has shown that consuming fish or fish oil can reduce depression, anxiety (1), hot flashes, and sleeping problems (2) in menopausal women. In addition, fatty fish is rich in vitamin D, which is essential for calcium absorption and maintaining bone health.
If you don’t eat fish, you can still get the benefits of n-3 PUFAs by consuming foods rich in α-linoleic acid (ALA), which our bodies can convert into these beneficial fatty acids. ALA has been shown to improve skin hydration and smoothness and can be found in foods like flaxseeds, almonds, walnuts, and chia seeds (1), as well as soy products that we’ll discuss later.
2. Olive leaf extract for menopausal symptoms
Olives contain (poly)phenolic compounds that have many positive effects, including antioxidant, anti-inflammatory, and anticancer properties (3).
Interestingly, olive leaves contain significantly higher concentrations of phenolic compounds than olives or olive oil (4). As a result, they may have even greater potential for exerting beneficial effects on health. In fact, research has already demonstrated that taking olive leaf extract daily can be an effective alternative treatment for reducing blood pressure in individuals with hypertension (5).
One of the key phenolic compounds found in olive leaf extract is oleuropein, which has been shown to significantly impact women’s health during post-menopause. Oleuropein has been proven to reduce cholesterol levels, lower the risk of bone loss, alleviate joint pain, improve skin health and enhance mobility (6,7).
Bonolive® is an olive leaf product that is standardized for high levels of oleuropein.
3. Soy products
Soy products, including soy milk, soybeans, and tofu, are rich in isoflavones, which are plant-derived estrogens and selective modulators of estrogen receptors in the body. These properties make soy products a promising alternative to hormonal therapy.
Soybeans contain essential fatty acids, such as ALA (α-linoleic acid), that have anti-inflammatory properties. Additionally, soy protein has been found to reduce bad cholesterol levels, which can lower the risk of cardiovascular diseases (8).
One of the isoflavones found in soybeans is genistein, which is structurally similar to female estrogen and can alleviate menopausal hot flashes. Another isoflavone, daidzein, can inhibit cell proliferation in the gastrointestinal tract, potentially reducing the risk of estrogen-sensitive cancers, such as ovary, prostate, and breast cancer (9).
4. Yogurt to support menopause
Yogurt is a nutrient-rich food that contains calcium and vitamin D, which are important ingredients to improve bone health during menopause. Bifidobacterium bifidum and Lactobacillus acidophilus, which are considered ‘good’ bacteria, are used to make yoghurt and they are also present in the final product, making yogurt a source of probiotics that can benefit gut health.
Research has shown that consuming extra probiotics in yogurt can help to reduce anxiety and stress levels, and improve overall quality of life compared to regular yogurt (10). However, regular yogurt also has similar long-term effects. Additionally, yogurt may have a role in appetite control, making it a helpful food for weight management (11).
Studies have suggested that a well-balanced diet that includes milk and dairy products, like yogurt, may also improve sleep quality (12).
How can foods help with menopause symptoms?
To summarize, consuming fish, soy products, whole grains, olive leaf extract, and yogurt can promote healthy cholesterol levels, maintain bone mass, reduce menopausal symptoms such as hot flashes and mood swings, and help regulate appetite and blood sugar levels. If you’re experiencing menopausal symptoms, these natural products are worth considering.
The BioActor website transitioned into a new Solabia Nutrition website
Solabia Nutrition, formerly known as BioActor, transitioned to a new website
Last updated: 10th April, 2024
We are announcing an important development for our valued customers and partners:
The BioActor website transitioned to a brand new Solabia Nutrition website
Joining the Solabia Nutrition family marked a significant milestone in the BioActor journey. As part of this strategic move, we are excited to inform you that the BioActor website is now transformed into a brand new Solabia Nutrition website at www.solabianutrition.com
This transformation represents our commitment to delivering premium nutritional solutions to the health and wellness industry, backed by science. By consolidating our online presence under the Solabia Nutrition brand, we aim to streamline your experience and offer seamless access to our comprehensive portfolio of products and services.
Stay tuned for updates as we work to ensure a smooth transition and provide you with enhanced resources to support your nutritional goals.
If you have any questions, do not hesitate to get in touch!
4 reasons to include Naxus® in your gut health formulation
4 reasons to include Naxus® in your gut health formulation
Arabinoxylans are essential prebiotics that exert beneficial effects on human health, particularly gut health. The relationship between diet and gut health has gained popularity in the last decades, with promising research emerging at an increasingly rapid pace. For product developers, it can be challenging to decide which ingredients to include in their gut formulation. In this article, you will discover 4 compelling reasons to include Naxus® in your gut health formulation.
What is Naxus®?
Naxus® is a patent-protected, prebiotic arabinoxylan extract sourced from the wheat endosperm. It can boost the immune system and improve gut health.
Solabia-BioActor developed Naxus® and conducted extensive research in collaboration with Maastricht University, Wageningen University & Research, Institute Pasteur and more, demonstrating its positive effects in numerous studies.
Clinical research in diverse populations shows that Naxus® promotes gut health by improving intestinal barrier function, increasing beneficial micro-organisms (e.g., Bifidobacteria and Bacteroides), improving the short-chain fatty acid (SCFA) profile and inducing cytokine and chemokine production (1, 2, 3).
Naxus® exerts its beneficial effects at doses starting at 1 g. Click below to see the scientific evidence.
4 reasons why Naxus® is a great addition to gut health formulations
If you are considering including Naxus® in your formulation for gut health, you should consider the following aspects:
1. Naxus® improves SCFA profile and strengthens the gut barrier
Health-promoting micro-organisms are present in the gut and help to protect the gut wall from pathogens and bad bacteria. Studies have demonstrated that Naxus® supports the growth of beneficial microbiota (1). Consequently, these microbiota produce advantageous SCFAs like propionate and butyrate.
SCFA production is related to a variety of positive health effects. To illustrate, these metabolites reduce the risk of developing inflammation and promote psychological and physical health. Moreover, they regulate the host immune system and improve metabolic health (4, 5).
2. Naxus® supports the immune system
Naxus® has proven immunomodulatory properties by enhancing gut barrier integrity and improving the adaptive and innate immune system.
Research indicates that Naxus® improves multiple gut barrier parameters such as reduced intestinal permeability, increased goblet cell number, and higher intestinal immunoglobin A concentrations (6).
Additionally, Naxus® has been shown to increase vaccination efficacy against influence resulting in fewer adverse events, fewer respiratory tract infections, and improved seroprotection rates (7).
Moreover, Naxus® improves the innate immune system, leading to an increased immune system vigilance (2, 3).
3. Naxus® is slowly fermentable without bloating
Naxus® is composed of long and complex carbohydrate molecules, that ferment slowly and gradually (8). Therefore, Naxus® has an advantage over other fibres like inulin, because it does not cause intestinal complaints such as bloating and gas formation in the gut.
4. Naxus® can be used in many formulation types
Arabinoxylans, with their favourable physicochemical properties, have been successfully incorporated into numerous food products. Naxus® is wheat-derived and gluten-free and is therefore suitable for various formulations.
Naxus® has an emulsifying capacity and influences the viscosity of multiple foods. Its effects have been tested in products such as pasta, bread, beer, cakes, and cookies. For example, in the bread-making processes, arabinoxylans positively affect dough consistency, loaf volumes, crumb structure, and bread staling.
These beneficial technological characteristics prove the potential to include Naxus® in any gut health formulation.
Naxus®, the key ingredient for your gut health formulation
Naxus® contributes to your gut health by improving the microbiome, protecting the intestinal gut barrier, and supporting the immune system. It is a patent-protected product that bears an EFSA claim for reduction of post-prandial glycemic response and can be incorporated into multiple food products due to its beneficial properties.
Its innovative and science-based nature makes it a valuable addition to optimise your gut health formulation!
Which ingredients should a pre-workout formula include?
The best ingredients for a pre-workout
Last updated: March 6th, 2024
If you are looking for the ideal pre-workout formula, you came to the right place. In this article, we explore the most relevant ingredients that your pre-workout should include to target power, focus and endurance.
Many gym-goers seek pre-workout supplements to enhance performance, but choosing the right ingredients remains a challenge.
In this article, we explore a few effective ingredients to target the 3 main benefits a high-quality pre-workout should provide: power, focus and endurance.
What is a pre-workout?
These formulations are combinations of ingredients, designed to boost energy and performance. That’s why athletes from all disciplines typically consume them shortly before their workout or training.
The goal of consuming these formulas is to enhance acute exercise performance [1]. You can find pre-workouts in different forms, like drinks, gels or capsules, yet ready-to-drink powders are by far the most common format.
Essential aspects of a pre-workout
If you consider consuming a pre-workout to improve your performance, there are a few things to take into account before making a purchase.
Firstly, you want an effective product that delivers three main benefits: power, focus and endurance.
Secondly, choosing a product that provides rapid onset of these effects is important, ideally within 15-30 minutes of intake.
Lastly, it is best to select a formula that contains natural ingredients and avoid consuming high amounts of stimulants like caffeine.
In the next section, we look at the ingredients that you should look for in a pre-workout.
Ingredients for power
These ingredients enhance muscular strength and power, optimizing performance during workouts [2].
Citrulline malate
This ingredient consists of citrulline, a non-essential amino acid, and malic acid, an intermediate in the citric acid cycle.
Citrulline malate may improve blood flow during exercise by augmenting nitric oxide (NO) levels, as citrulline is a NO precursor [3].
Currently, it is unclear whether the performance improvement is linked to this mechanism, but several studies support an improvement in peak power output after citrulline malate consumption [4,5].
Creatine
Creatine is one of the most well-researched ingredients in sports nutrition. This ingredient increases intramuscular creatine levels. Short-term energy generation in muscle tissue comes virtually 100% from creatine – the phosphorylated isoform, Cr-P.
Daily intake of 3 g promotes anaerobic performance in the gold standard Wingate Test [6]. Furthermore, researchers found beneficial effects on exercise recovery with creatine intake, reducing exercise-induced muscle damage [7].
Ingredients for focus
These ingredients ensure that you can focus on your movements to execute them with high precision [2]. Focus is commonly referred to as the mind-muscle connection.
Brainberry®
If you are looking for an alternative to caffeine to boost your focus, you might want to learn more about Brainberry®.
Brainberry® is a natural Aronia berry extract developed by BioActor to enhance cognitive performance. Research revealed that the consumption of Brainberry® increases focus, psychomotor speed and mental flexibility [8,9].
In particular, a study on 35 professional basketball players, showed important benefits after one week of supplementation. This study highlighted the ability of Brainberry® to significantly enhance cognitive performance and improve basketball-specific skills like shooting, rebounding and dribbling.
Cyanidin-3-O-Galactoside is the active ingredient in Brainberry® and plays an important role in improving brain health and cognitive functions.
Want to know more about Cy3Gal, and how it is involved in brain health? Read this article!
Caffeine
Caffeine is another ingredients that is well-researched in sports nutrition [2]. It is known for its ability to provide acute ergogenic effects.
A daily dose of 3 mg/kg bodyweight is linked to improvements in alertness, vigilance, mood and cognitive processes during exercise [10].
However, a comparison between non-caffeine and caffeine-containing pre-workout formulas concluded that the caffeine-containing pre-workout reduces calmness. If you are training in the evening, this might be a reason to pass on caffeine [11].
Ingredients for endurance
These ingredients are important to provide nutrients to feel energized until the end of your workout [2].
Beta-alanine
Beta-alanine is a carnosine precursor, a compound that buffers lactate build-up in the muscle tissue, prolonging the feeling of soreness.
It has been shown that 4-6 g of beta-alanine consumption per day for two weeks improves high-intensity exercise performance. Regular consumption maintains a certain level of intramuscular carnosine levels, as beta-alanine is the limiting factor in carnosine production [12].
Carbohydrates
Carbohydrates play a crucial role in providing sustained energy levels during prolonged exercises. However, the amount needed depends on the type of exercise [13]. For typical gym sessions lasting between 45 to 120 minutes, consuming a small amount of rapidly absorbed carbohydrates shortly before exercise can be beneficial.
For longer endurance activities, such as marathon training or extended cardio sessions, a larger intake of carbohydrates is necessary to optimize performance [14]. Slow-release carbohydrates could be a consideration for endurance athletes.
Citrus flavonoids – For power and endurance
If you want to take your pre-workout to the next level, an additional ingredient you may want to include in your pre-workout formula is citrus flavonoids (hesperidin).
WATTS’UP® is a natural Citrus sinensis extract researched and developed by BioActor. The recommended daily dose (clinical dose) for this ingredient is 400-500 mg.
Two randomized placebo-controlled clinical trials conducted by BioActor confirmed that WATTS’UP® can significantly improve peak force, endurance capacity and anaerobic power in trained subjects.
Further research revealed that WATTS’UP® works by stimulating nitric oxide (NO) synthesis in blood vessels, thus stimulating vasodilation and better blood flow. [15]
Moreover, it was demonstrated that WATTS’UP® boosts mitochondria efficiency and respiration capacity. This resulted in 33% higher ATP production – the fuel for our muscles [16].
Therefore, WATTS’UP® would be a great addition to any sports nutrition supplement.
Conclusion
In conclusion, pre-workouts are tailored combinations of ingredients aimed at enhancing energy and performance for athleses across various disciplines. Each ingredient serves a specific function, contributing to distinct aspects of sports performance.
Citrulline malate and creatine are dedicated to increase power, whereas Brainberry® and caffeine improve focus. Furthermore, beta-alanine and carbohydrates are valuable ingredients to enhance endurance performance.
Lastly, citrus flavonoids, such as WATTS’UP®, offer a promising dual benefit for any pre-workout formulation by boosting both power and endurance.
Discover YAMAMOTO’s Success Story
Learn how YAMAMOTO integrated WATTS’UP® into their products, driving remarkable success.
FDA GRAS Approval for Bonolive®
Bonolive® – Solabia-BioActor’s innovative women’s health ingredient, receives FDA GRAS approval
PRESS RELEASE
The United States Food and Drug Administration approves Bonolive® as safe for inclusion in supplements, beverages and functional foods.
Solabia-BioActor received а no objections letter from the U.S. Food and Drug Administration (FDA) regarding their Generally Recognized as Safe (GRAS) application for its women’s health ingredient Bonolive®. The FDA approves Bonolive® for inclusion in Dietary Supplements, Beverages and Functional Foods.
For access to the FDA “no objection letter” please follow this link.
GRAS is a designation created by the FDA under the Federal Food, Drug and Cosmetic Act. It is a testament to the safety of a food ingredient or additive based on adequate evidence. Bonolive® had already shown a clean safety profile in published tox studies and a GRAS panel had concluded that Bonolive® should be considered GRAS.
Bonolive® is an oestrogen-free, patented ingredient, standardised for high levels of oleuropein. This all-natural ingredient is clinically validated in post-menopausal women to support women’s health during post-menopause. Human intervention studies showed that Bonolive® plays a key role in:
- stimulating bone-building cells (osteoblasts) and stabilising bone mineral density
- improving blood lipid profile
- reducing joint pain and improving mobility.
A recent consumer study in menopausal women also showed that Bonolive® helps alleviating menopause related symptoms related to mood and skin appearance. Interestingly, a pharmacokinetics study showed that Bonolive® has an enhanced bioavailability in post-menopausal women.
Bonolive® targets women in peri- and post menopause that are looking for a safe, natural and oestrogen-free solution to the challenges of menopause. It is a true innovation as the only clinically evaluated olive leaf extract for women’s health. This ingredient is now also available in a convenient RTD format for everyday easy intake.
Feel free to contact us via info@bioactor.com for more information on the possibilities Bonolive® has to offer.
Further information can be found on: www.bonolive.com
About Solabia Nutrition
Solabia Nutrition, a part of Solabia Group, is a product development company that has developed a range of proprietary bioactive formulations with clinical studies. Based in Maastricht, the Netherlands, the company focuses on the development of innovative bioactives that address active living and healthy ageing. The goal is to provide the nutrition & healthcare industry with science-based innovations that confer a real health benefit to the consumer.