Brainberry, benefits of aronia berries

The health benefits of Aronia Berry

The health benefits of Aronia Berry: why should you consume this superfruit?

Last updated: February 9th, 2024

September 1st, 2021

Aronia berries are small dark fruits that are becoming increasingly popular amongst health-conscious consumers. Current research suggests that due to their excellent content in micronutrients and antioxidant properties, these berries may provide important health benefits on immune health, cardiovascular function, brain health as well as exhibiting anti-diabetic function.

Brainberry, benefits of aronia berries

What is Aronia berry?

Aronia berries are little dark fruits, belonging to the Rosaceae Family. Aronia is native to Eastern and North America but it is also commonly found in the Baltic region of Europe where it was introduced in the first half of the 20th century.

The reason why these berries are also called “Chokeberries” is that when consumed fresh off the shrub, they make your mouth tickle due to their incredibly strong tart taste and mouth-drying effect.

Though many people have never heard about them, Aronia berries are becoming increasingly popular among health-conscious consumers and are considered a real superfruit.

What are the health benefits of Aronia berries?

To answer this question we need to first take a step back in the past where Aronia was traditionally used by the North American Forest Potawatomi tribe as a cold remedy.

They called these fruits “nîki’mînûn” and used them to make a traditional tea. The reason why Aronia berry was found to be so effective in treating common cold symptoms is probably linked to their extremely powerful antioxidant capacity.

Nowadays, it is well-known that antioxidants in Aronia outperform any other fruits, even elderberries, blueberries, and raspberries.

Aronia berries contain high levels of vitamin C, but the real claim to fame is their high level of polyphenols, anthocyanins and proanthocyanins [1]. These are types of antioxidants that help to fight the damages caused by free radicals in the body, and it is these antioxidants where Aronia berries can have their greatest impact on our health and wellbeing.

Aronia Antioxidant

In fact, Aronia is considered a real superfruit due to its high level of antioxidant phytonutrients that can be beneficial in many ways.

Research around Aronia berries has focused on several health benefit areas, and there is evidence to suggest that these fruits may have the potential to:

 

  • Strengthen the immune system [2]
  • Improve cardiovascular function [3]
  • Improve brain health [4]
  • Help against metabolic syndrome [5]
  • Prevent urinary tract infections [6]
  • Support cognition and eye health

Nutritional Facts

Aronia berries are low-calorie fruits, full of important micro-nutrients accountable for their numerous health benefits.

100 g of Aronia berries provide the following nutrients [7]:

  • Calories: 47.0 (197 kJ)
  • Carbs: 9.6 g
  • Fat: 0.5 g
  • Protein: 1.4 g
  • Fiber: 5.3 g
  • Vitamin A: 350 IU (7% DV)
  • Vitamin C: 21 mg (35% DV)
  • Vitamin K: 13.6 mcg (17% DV)
  • Manganese: 0.6 mg (32% DV)

Moreover, researchers have identified a total of 7 different anthocyanins in Aronia berries. These include phytocompounds such as cyanidin-3-O-glucoside, a key molecule for brain health. It has been reported that cyanidin-3-O-glucoside exhibits anti-inflammatory, anticarcinogenic and antimutagenic activities, while also enhancing spatial memory, cognition and psychomotor control.

How to get more Aronia berries in your diet

Unfortunately, it is not easy to commonly find fresh Aronia berries on the shelf at the grocery store.

However, there are many alternatives. Especially in specialised stores or online, it is possible to buy Aronia in the form of frozen or dried fruits, tea, jams, juice and wines.

Another effective way to include Aronia in your diet can be through the use of dietary supplements. This can be a great way to ensure you are getting the most out of the health benefits of Aronia berries.

Curious to know more? Here’s everything you need to know about Aronia berries and brain health!


2023 Recap & Plans for 2024

2023 Recap & Plans for 2024

December 5th, 2023

As 2023 is coming to an end, we take a moment to reflect on our work and achievements of the year. 

Our dedicated team actively participated in 17 international events, contributed to academia by publishing four scientific papers in international peer-reviewed journals, and initiated two promising research collaborations.

In addition, our team had regular monthly business trips and numerous productive client meetings. These accomplishments stand as a testament to our collective efforts and dedication to our work, providing high quality, science-based nutrition solutions.

solabia bioactor 2023

With gratitude, we reflect upon the accomplishments of 2023 and we are looking forward to what lies ahead in 2024.

Here we share a brief glimpse into what the upcoming year holds:

  • 6-7 March: Nutraceuticals Europe, Barcelona
  • 14-16 May: VitaFoods Europe, Geneva
  • 18-20 September: VitaFoods Asia, Bangkok
  • 30-31 October: SupplySide West, Las Vegas

 

Get in touch!



    heart health and food and cordiart

    What are the best ingredients for heart health?

    What are the best ingredients for heart health?

    Maastricht, 5th December 2023

    Cardiovascular health is vital for longevity. Lifestyle factors, including regular exercise and a heart-healthy diet, are crucial for maintaining cardiovascular well-being. Omega-3 fatty acids, soluble fibers, vitamins, and polyphenols in the diet play key roles in regulating blood pressure and cholesterol levels. Find out more about keeping your heart healthy.

    ingredients to improve heart health

    The cardiovascular system

    Maintaining cardiovascular health is essential for a long and active life (1). The cardiovascular system consists of the heart, arteries and veins in the human body.

    There are two important blood transportation systems: the pulmonary circulation and the systemic circulation. The pulmonary circulation transports deoxygenated blood to the lungs, to allow the exchange of carbon dioxide for oxygen by the lungs. The second system is the systemic circulation, which transports nutrient- and oxygen rich blood to all organs and cells (2). Therefore, both systems contribute to delivery of oxygen blood to tissues from head to toe. This is essential because every single cell in the human body needs oxygen and nutrients to maintain energy production.

    How can nutrition impact cardiovascular health?

    There are several factors that can influence the well-being of cardiovascular health. Stress is a major player in changing blood flow. It can temporarily increase blood pressure and heart rate. Over time, chronic stress can lead to persistent high blood pressure, inflammation, and the buildup of fatty deposits in the arteries, a condition known as atherosclerosis. (3)

     

    On the other hand, regular exercise and physical activity help improve heart and blood vessel function, lower blood pressure, reduce cholesterol levels, and maintain a healthy weight.

     

    Another factor that impacts cardiovascular health, is diet. A “heart-healthy” diet is low in saturated fats, cholesterol, salt, and added sugars, and high in fruits, vegetables and whole grains. Food directly impacts the health condition of your heart. If you choose the right foods, you can help to keep your heart in good shape. (4).

     

    These heart-healthy foods help to reduce inflammation, lower blood pressure, and maintain healthy blood vessels. Here are a few great options:

     

    Healthy fats, found in olive oil, avocados, and fatty fish like salmon, are integral to cardiovascular health. They promote optimal cholesterol profiles and reduce the risk of blood clots.

    Legumes like beans, chickpeas and lentils, aid in lowering cholesterol levels and blood pressure. The health effects of this food are typically attributed to the high content of fiber, nutrients, and active plant compounds (5).

    Fruits that contain high levels of polyphenols – a complex group of secondary plant metabolites. There is growing evidence that suggests that polyphenols could be relevant compounds for improving heart health. Notably, certain varieties of citrus fruit are known for their high levels of antioxidants, which play a role against oxidative stress (6, 7).

    cordiart heart health ingredients

    Key ingredients for heart health

    Some people are limited in choosing their food, because of limited availability, so they may not be able to consume a diet rich in abovementioned foods. Supplementation could be a feasible alternative to consume the crucial compounds from those foods for supporting cardiovascular health. Therefore, we will now have a deeper look into the effective compounds, which can be easily supplemented:

     

    Omega-3 fatty acids are an example of healthy fats. They can be found in a lot of retail channels, pharmacies or online, predominantly in soft gels. They reduce the amount of triglycerides and improve cholesterol levels by lowering LDL cholesterol and increase the good HDL cholesterol. Moreover, omega-3 regulate blood pressure and have anti-inflammatory properties.

    Soluble fibers, normally found in fruits, legumes, vegetables and grains. They bind to cholesterol and remove it from the body. In this way, cholesterol levels can be reduced (8). Examples of soluble fibers to look for in terms of supplementation are psyllium, pectin and wheat dextrin.

    Vitamins can help to improve heart health. For example, there is high-quality research showing that Vitamin B9 supplementation can reduce the risk of stroke and cardiovascular disease (9). Moreover, Vitamin K2 serves an important role in cardiovascular health through regulation of calcium homeostasis. It can lead to a reduction in arterial stiffness (10).

    Citrus flavonoids are a group of polyphenols that are, unsurprisingly, found in citrus fruits. Flavonones are a subclass of flavonoids that are linked to an improvement in heart health. Specifically, hesperidin (hesperitin-7-O-rutinoside), offers several health advantages due to its anti-inflammatory and antioxidant properties, potentially playing a role in cardiovascular health (11). Some studies suggest that hesperidin may help lowering blood pressure and improving blood vessel function, which can be beneficial for heart health (12).

     

    BioActor has developed Cordiart®, a proprietary sweet orange extract that is high in the rutinoside hesperidin. Cordiart® has the potential to support heart health by improving blood vessel function, reducing inflammation, and helping to manage high blood pressure. It can also assist in lowering LDL cholesterol levels. The beneficial effects of Cordiart® on endothelial function are clinically proven (13, 14).


    improving-cardiovascular-health

    Simple ways to boost your cardiovascular health

    Simple ways to boost your cardiovascular health

    May 10th, 2023

    Cardiovascular health refers to the health of the cardiovascular system. Its definition is based on all the behaviors and health factors that, when optimal, are associated with better cardiovascular disease-free survival and quality of life. Choosing a healthy diet, being more active, and maintaining normal blood lipid and glucose levels are some of the strategies that help to maintain great cardiovascular health throughout our lives.

    improving-cardiovascular-health

    How to define cardiovascular health?

    The American Heart Association has provided a number of metric definitions that can be used to classify poor, intermediate, or ideal cardiovascular health. These include diet, physical activity, smoking, sleep, weight, blood and glucose levels, and blood pressure.

    Pursuing a healthier lifestyle from a young age is a great strategy for maintaining ideal cardiovascular health throughout our lives. This will result in a lower risk of developing cardiovascular diseases such as hypertension, strokes, atherosclerosis, peripheral artery disease, and vein diseases (1).
    In this article, we will dive into the 7 ways to improve your cardiovascular health!

    Healthy eating behaviors

    Creating a healthy eating pattern represents an easy way to improve your cardiovascular health. This means preferring certain foods such as vegetables, fruits, whole grains, plant-based proteins, fish and limiting sweetened drinks, alcohol, full-fat dairy products, and highly processed foods.

    Avoiding trans-fat and partially hydrogenated oils that are contained in many commercial baked goods represents another good and easy strategy to improve your eating habits (1).

    Polyphenols derived from olive leaves also have many beneficial effects and represent a promising, natural ingredient for supporting cardiovascular health (2).

    Giving up smoking

    Smoking is deleterious for your circulatory system as it increases the risk of stroke in both men and women. Cigarettes, e-cigarettes, and tobacco products contain many toxic chemicals, as do their smoke, and liquids. Several beneficial changes occur after quitting smoking and within one year after quitting, your risk of heart disease goes down with 50% (1).

    Physical activity

    Regular exercise and physical activity are associated with remarkable health benefits. Adults should do at least 150 minutes of moderate-intensity aerobic activity a week or 75 minutes of vigorous aerobic activity or a combination of both, throughout the week. Parking further away from your work place or taking the stairs instead of the elevator contributes to physical activity levels and improves health outcomes (1).

    Sleep quality

    Sleep plays a crucial role for overall health and well-being. Short sleep duration or poor sleep quality is associated with high blood pressure, elevated cholesterol levels, and atherosclerosis. These conditions can be prevented by aiming for an average of 7-9 hours of quality sleep a day (1).

    Body weight management

    Maintaining a healthy weight, defined as a body mass index between 18.5 and 24.9 for adults, can help reduce the risk of many heart problems such as cardiovascular disease, stroke, and high blood pressure.
    A few strategies that can help to manage body weight include choosing a healthy diet, increasing physical activity levels, limiting alcohol, avoiding stress, and improving your sleep quality (1).

    Stable blood lipid and glucose levels

    Cholesterol is a fat-like substance that your body needs, in the right amounts, for good health. Unhealthy levels of cholesterol can lead to a higher risk of cardiovascular disease, such as heart disease and stroke. Checking your cholesterol levels regularly can help you understand whether you have normal blood lipid levels.

    Over time, high blood glucose levels can damage your health too. Blood glucose levels rise because of the glucose that enters the bloodstream and insulin, a hormone that helps the cells take up the glucose they can use for energy production.

    A healthy diet that includes vegetables, fruits, whole grains, beans, legumes, nuts, plant-based proteins, and lean animal proteins, may help you manage cholesterol and glucose levels. Other strategies include being more active, quitting smoking, and maintaining a healthy weight (3).

    Blood pressure control

    Blood pressure is defined as the pressure of your blood on the walls of the arteries as your heart pumps it throughout your body. When your blood pressure is permanently higher than normal, the risk of heart attacks and strokes increases.

    There are no signs or symptoms of high blood pressure, which means it is crucial to have regular check-ups to measure it. Simple changes to your lifestyle, such as eating healthy and being more active can help manage your blood pressure over time (4).

    How to improve your cardiovascular health?

    To summarize, choosing a healthy diet, quitting smoking, being more active, improving sleep health, maintaining normal blood lipid, and glucose levels, and managing your blood pressure are great strategies to lower the risk of developing cardiovascular disease thus, improving your cardiovascular health.


    Cordiart® and Bonolive®obtained registration by the Malaysian National Pharmaceutical Regulatory Agency

    Cordiart® and Bonolive®obtained registration by the Malaysian National Pharmaceutical Regulatory Agency

    Maastricht, The Netherlands, September 15th, 2017

    Press release

    Both Cordiart® and Bonolive® obtained registration by the Malaysian National Pharmaceutical Regulatory Agency. Both finished capsule products of which one containing Cordiart® and the other Bonolive® are now officially registered and can be sold on the Malaysian market.

    The Cordiart® and Bonolive® In Malaysia

    Cordiart® and Bonolive® containing finished capsule products, named Smoozflo and Bonee Care, have been officially approved and registered in Malaysia by the National Pharmaceutical Regulatory Agency. Cordiart® finished capsule products are registered to be used for improving blood circulation under registration number MAL16110075TC. Bonolive® finished capsule products are registered to be used to strengthen bones and joints under registration number MAL16060038TC.

     

    Both Cordiart® and Bonolive® have been clinically evaluated to have significant effects:

    Two studies have shown that Cordiart® provides a triple protection of the arteries by improving arterial flexibility, reduces plaque formation, and lower arterial inflammation. The first study targeted patients with metabolic syndrome and impaired endothelial function, whilst the second study was looking at healthy overweight people. In both studies Cordiart® increased flow-mediated dilation compared to placebo. In addition the second study showed a reduction of the levels of adhesion molecules, responsible for plaque formation, and a reduction of the levels of inflammation markers, reflecting the inflammatory status of the arteries.

     

    A 12-month double-blind, placebo-controlled study on a group of osteopenic patients consuming 250 mg/daily of Bonolive® showed a 32% significant increase in serum osteocalcin levels. This validates that Bonolive® prevents bone loss by strengthening bone metabolism and stimulating bone-building cell activity.

     

    If you are interested in these products please feel free to contact our distributor for the Malaysian market, Membra Health, at info@membra.com.my.

     

    About BioActor

    BioActor, based in Maastricht, Netherlands, is a product development company that has developed a range of proprietary bioactive ingredients for the nutrition & healthcare industry. The company focuses on the development of innovative activities that address active living and healthy aging. The goal is to provide the nutrition & healthcare industry with science-based innovations that confer a real health benefit to the consumer.

    Feel free to contact us via info@bioactor.com for more information on the possibilities Cordiart® and Bonolive® has to offer.
    Further information can be found on: www.cordiart.com and www.bonolive.com


    Clinical results published in a leading nutrition journal provide novel evidence supporting the beneficial effect of consumption of citrus flavanones on postprandial endothelial function.

    Clinical results published in a leading nutrition journal provide novel evidence supporting the beneficial effect of consumption of citrus flavanones on postprandial endothelial function.

    Maastricht, Netherlands, April 6, 2017

    Press release

    The British Journal of Nutrition has published results revealing that an acute, sole dose of citrus flavanones may counteract the transient decline in endothelial function, 7-hours postprandially. However, no effect was found 2-hours postprandially. This study corroborates findings from the latest clinical study on Cordiart®, a sweet orange extract. Moreover, it was shown that a repeated daily dose of standardized citrus flavanones may impart already 2-hours postprandially, a faster recovery in FMD response as compared to a sole dose.

    The Clinical Benefits of Cordiart®

    A recently published randomized, controlled, double-masked, crossover study (2017) has evaluated the acute impact (0-7 h) of flavanone-containing (mg) 240 ml beverages (orange juice: 128.9 mg; flavanone-rich orange juice: 272.1 mg; homogenized whole orange: 452.8 mg) on postprandial (Western diet/double meal with 81 g of fat) vascular function among middle-aged healthy men (30-65 years, N=28). Subjects had mild cardiometabolic risk factors with a baseline FMD (flow-mediated dilation) of 4.8 units and fasting lipids in the upper half of the normal range (TAG 0.8-3.2 mmol/l, total cholesterol 6.0-8.0 mmol/l) or BMI 25-32 kg/m2.

    After 2-hours postprandially, there was no detected improvement in % FMD for all three interventions, despite differing flavanone concentrations. By 7-hours postprandially, all interventions were able to attenuate temporary impairments in FMD to that of baseline levels (7-hours post intake, P<0.05). This was suggested to be due to probable actions of citrus flavanone metabolites on nitric oxide.

    Even though these results are promising, it can also be implied that an individual is exposed to endothelial dysfunction for up to 7-hours. By this time, it is common to have already consumed another meal (Western diet), reflecting that the majority of the day is spent in a postprandial state. This absence of a rapid postprandial effect may also be attributed to low flavanone bioavailability.

    The article concludes that a daily intake of citrus flavanones may be an effective dietary strategy and ‘such temporary vascular changes repeated on a daily basis can critically impact long-term vascular health and overall chronic disease risk

    Given the former, it’s important to have a rapid improvement in endothelial function postprandially. This was shown in a 6-week randomized, double-blind, placebo-controlled study that investigated the effects of a daily repeated intake of 500mg of Cordiart® on endothelial function. Already 2-hours after the consumption of a high-fat meal, 6-weeks of Cordiart® supplementation was shown to significantly increase and recover FMD (mean) by approximately 8.9% when compared to the mean baseline fasting level, in individuals with borderline chronic endothelial impairment (FMD≥3%). Therefore, Cordiart® may provide a faster recovery in FMD response as compared to a sole dose of non-standardized flavanones.

    Moreover, orange juice is known to contain a high amount of sugar and is not standardized for active flavonoid content. Overall, Cordiart® provides a standardized dose of flavonoids, serving as an optimal solution for preserving endothelial function and supporting healthy blood flow.

    About BioActor

    BioActor, based in Maastricht, Netherlands, is a product development company that has developed a range of proprietary bioactive ingredients for the nutrition & healthcare industry. The company focuses on the development of innovative activities that address active living and healthy aging. The goal is to provide the nutrition & healthcare industry with science-based innovations that confer a real health benefit to the consumer.

    Feel free to contact us via info@bioactor.com for more information on the possibilities Cordiart® has to offer.
    Further information can be found on: www.cordiart.com


    Hearth health

    BioActor’s Research Director Sam Possemiers Introduces Cordiart® at MIS 2014: 21-22 May, Quimper- France

    BioActor’s Research Director Sam Possemiers Introduces Cordiart® at MIS 2014: 21-22 May, Quimper- France

    Maastricht, The Netherlands, March 3rd, 2014

    Press release
    Cordiart® clinically shows high bioavailability and improvements in endothelial function proving to be a great rutinoside formulation for cardiovascular health. The results of the clinical trial will be discussed in more detail in the Molécules & Ingrédients Santé (MIS) by BioActor’s research director Dr. Sam Possemiers.

    Hearth health

    Cordiart® in the spotlight at Molécules & Ingrédients Santé

    For the 5th time, Molécules & Ingrédients Santé (MIS) will gather during 2 days industrial scientists, university researchers as well as experts to focus on last advances and future prospects in terms of new active ingredients, clinical tests and legislation.

    BioActor’s research director Dr. Sam Possemiers will give a lecture on BioActor’s innovative cardiovascular ingredient Cordiart®. Cordiart®, a specific rutinoside formulation for cardiovascular health, has shown strong clinical data on the improvement of endothelial function. Cordiart® stimulates the eNOS-enzyme which plays a pivotal role in the synthesis of Nitric Oxide, one of the most important regulators of vascular elasticity. Parties have completed a pharmacokinetics study showing the high bioavailability of Cordiart®.

    MIS 2014 will take place in Quimper, capital city of Cornouaille with a high industrial, R&D and training potential in the fields of nutrition and marine ingredients. The health products field still represents a strong profitable industry with a US $11 billion global market and a 5% annual growth. In the same time, dietary supplements turnover is now exceeding US $50 billion in spite of recent regulatory limitations. In this context and because of stronger requirements of consumers regarding efficacy of ingredients, innovation remains the keystone of this high value-added economy.

    About BioActor

    BioActor, based in Maastricht, Netherlands, is a product development company that has developed a range of proprietary bioactive ingredients for the nutrition & healthcare industry. The company focuses on the development of innovative activities that address active living and healthy aging. The goal is to provide the nutrition & healthcare industry with science-based innovations that confer a real health benefit to the consumer.

    Feel free to contact us via info@bioactor.com for more information on the possibilities Cordiart® has to offer.
    Further information can be found on: www.Cordiart.com


    Metabolic Syndrome

    BioActor receives EUROSTARS grant for the FlaMeS project “Flavonoids and metabolic syndrome”

    BioActor receives EUROSTARS grant for the FlaMeS project “Flavonoids and metabolic syndrome”

    Maastricht, The Netherlands, October 22th, 2012

    Press release
    BioActor leads the international FlaMeS-consortium to develop novel in-vitro cell technology and clinical validation of Cordiart® for the prevention of the metabolic syndrome. The FlaMeS consortium is a collaboration between two innovation driven SMEs, BioActor (Netherlands) and AdipoPhyt (France). The project will result in the development and clinical validation of novel 3-D cell assays for adipose tissue development and in the clinical validation of a proprietary citrus flavonoid extract for the improvement of glycaemic control and endothelial function.

    Metabolic Syndrome

    The FlaMeS project

    BioActor BV announced today that EUREKA has approved the FlaMeS project, submitted by BioActor and AdipoPhYt. The FlaMeS Consortium has two objectives: (1) validating novel 3-D cell-based assays to screen for effects of compounds on adipose tissue development, and (2) clinically test and validate effects of Cordiart®, a citrus peel extract, on markers associated with the metabolic syndrome.

    Prevalence of obesity and the metabolic syndrome is rapidly increasing, affecting millions of people in Europe alone. Public health authorities have recognized the need for prevention of these chronic diseases. BioActor addresses this need by developing a unique, natural product for improved functioning of blood vessels, glycemic control and heart health: Cordiart®.

    Cordiart® is a natural flavonoid citrus peel extract with optimized bioavailability. This ingredient commands a high content of natural bioactive flavonoids. A number of in-vivo and human studies have shown very promising effects for Cordiart® in use for blood vessel function, glycemic control and heart health.

    In order to test novel substances regarding their effects on adipose tissue (fat storage cells), new ‘humanized’ in vitro models are needed. AdipoPhYt is currently developing a cutting edge new technology “AdipoGut”, combining all present techniques and knowledge into a high quality and predictive test system. The FlaMeS project will result in a marketable functional food ingredient “Cordiart®”, with proven beneficial effects on blood flow, glycemic control and heart health and a cutting edge new in vitro screening technology.

    “We are very happy with the Eureka/Eurostars commission’s trust in our project, as this clearly shows that they recognize our serious efforts in developing cutting edge food ingredients and food development technology at BioActor and our partner AdipoPhYt. This grant will enable us to further enhance our scientific knowledge on the effects of polyphenols on the human body and validate our product Cordiart®, which may even revolutionize the health market in cardiovascular disease prevention,” says Hans van der Saag, CEO BioActor.

    About BioActor

    BioActor, based in Maastricht, Netherlands, is a product development company that has developed a range of proprietary bioactive ingredients for the nutrition & healthcare industry. The company focuses on the development of innovative activities that address active living and healthy aging. The goal is to provide the nutrition & healthcare industry with science-based innovations that confer a real health benefit to the consumer.

    Feel free to contact us via info@bioactor.com for more information on the possibilities Cordiart® has to offer.
    Further information can be found on: www.cordiart.com