How can we support mitochondrial function?

Maastricht, 14th April, 2024

Supporting mitochondrial function is essential for maintaining overall health. Mitochondria serve as the cell’s powerhouses, responsible for energy production. Thus, maintaining mitochondrial health is key to cellular vitality and well-being.

Hesperian supports mitochondrial function

The Key to Enhanced Mitochondrial Function

Hesperidin, a flavonoid abundant in citrus fruits (1), exerts multiple positive effects within cells. It acts as an effective scavenger of free radicals, safeguarding cells from oxidative damage. Specifically, hesperidin impacts mitochondrial function through several pathways:

 

Enhanced Efficiency: Research suggests hesperidin can boost mitochondrial efficiency, leading to improved cellular energy production (2).

Mitochondrial Protection: Hesperidin’s antioxidant properties are pivotal in shielding mitochondria from oxidative damage. It scavenges harmful radicals and helps preserve mitochondrial integrity, preventing dysfunction induced by oxidative stress (3).

Improved Resilience: Studies suggest hesperidin enhances mitochondrial resilience against various stressors, including environmental toxins and metabolic challenges (3). By reinforcing mitochondria’s adaptive capabilities, hesperidin supports overall cellular health and longevity.

Reduced Inflammation: Chronic inflammation can compromise mitochondrial function and induce cellular damage. Hesperidin’s anti-inflammatory properties help mitigate inflammation, indirectly supporting mitochondrial health (4).

Cardiovascular Benefits: Some research indicates hesperidin may support cardiovascular health by enhancing mitochondrial function in cardiac muscle cells (5), potentially improving heart function and overall cardiovascular wellness.

Incorporating hesperidin-rich foods or supplements into your diet may provide a natural means to support mitochondrial health and enhance overall well-being.

 

How to Support Mitochondrial Health?

Various lifestyle choices can elevate hesperidin levels in the body, promoting overall health:

  • Dietary Choices: Consuming a diet abundant in citrus fruits is the primary strategy to boost hesperidin intake (6). Oranges, lemons, and grapefruits are excellent sources of this flavonoid. Incorporating these fruits into daily meals or snacks can significantly elevate hesperidin levels.
  • Fresh and Whole Foods: Opt for fresh and minimally processed foods to maximize hesperidin content (7). Freshly squeezed citrus juices and whole citrus fruits contain higher hesperidin levels than packaged or processed alternatives.
  • Cooking Methods: Choose cooking methods that preserve hesperidin content. Lightly steaming or stir-frying vegetables retains more hesperidin compared to boiling, which can leach out the flavonoid.
  • Supplementation: Hesperidin supplements, available as capsules or tablets, offer a concentrated source for those not getting enough through diet alone (8).
  • Physical Activity: Regular exercise can increase the bioavailability of flavonoids like hesperidin. Exercise improves blood circulation and metabolism, potentially enhancing hesperidin absorption and utilization.

 

Conclusion

Overall, hesperidin emerges as a valuable natural compound with the potential to support mitochondrial health and counteract oxidative stress-related disorders. Incorporating hesperidin supplementation or making dietary changes to increase hesperidin intake can further amplify these positive effects.