Clinical and pre-clinical data on MicrobiomeX® now published in a peer-reviewed journal

Maastricht, The Netherlands, July 11th, 2019

Press release
Nutrients, peer-reviewed journal of human nutrition, has published a systematic review on ‘flavobiotics’ – citrus flavonoids – and their effects on the microbiota and gastrointestinal health. The review includes original research data obtained with MicrobiomeX®. MicrobiomeX® is a natural citrus flavonoid complex designed to support gut and immune health, by lowering gut inflammation and beneficially shifting the gut microbiome composition.

microbiomex systematic review

The Systematic Review of MicrobiomeX®

Nutrients have published a systematic review on ‘flavobiotics’ – citrus flavonoids – and their effects on gastrointestinal health. The review includes original in-vitro and in-vivo data on MicrobiomeX®.

MicrobiomeX® is a first-in-class Flavobiotic® that protects the gut barrier and directly leverages the gut microbiome’s potential, enhancing the immune system. MicrobiomeX® is standardized for the two active citrus flavonoids: Hesperidin and Naringin.

The purpose of this systemic review article on citrus flavonoids and gut health was to provide a detailed overview of the intestinal metabolism of citrus flavonoids, their interaction with the gut microbiota composition, and their positive effect on the host barrier function and gut inflammation.

The review article also includes the outcomes of a 12-week randomized, parallel, double-blind, placebo-controlled study in which the effect of MicrobiomeX® on the gut microbiome composition, short-chain fatty acid production and gut inflammation was assessed. The study was conducted in a group of 50 healthy subjects with overweight, low background chronic gut inflammation and a somewhat disturbed microbiota.

The results showed
MicrobiomeX® anti-inflammatory activity as a result of a cross-talk between the active citrus flavonoids and the gut microbiome composition. Indeed, a significant increase in the butyrate proportion of total SCFA was measured, and an almost significant reduction in calprotectin levels are signs of the positive contribution of MicrobiomeX® to a balanced microbiome and host gut health.

MicrobiomeX® can already be found as a stand-alone ingredient or in combination with different probiotic strains, in several products worldwide. It can be applied in various finished dosage forms, including capsules, tablets, RTD sachets and beverages. MicrobiomeX® is the ideal candidate to bring cutting edge science from the microbiome revolution to nutritional formulas.

About BioActor

BioActor, based in Maastricht, Netherlands, is a product development company that has developed a range of proprietary bioactive ingredients for the nutrition & healthcare industry. The company focuses on the development of innovative activities that address active living and healthy ageing. The goal is to provide the nutrition & healthcare industry with science-based innovations that confer a real health benefit to the consumer.

Feel free to contact us for more information on the possibilities MicrobiomeX® has to offer.

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